In today’s news on 3D printing, Oerlikon and the Technical University of Munich are jointly founding a cutting-edge manufacturing institute. In bioprinting news, Fluicell has just launched a new system, a China-based joint research team has developed a six-axis bioprinting platform, and Cellink will work on scaling up of CollPlant’s breast tissue regenerative platform. Next, the Iowa State researchers tested their new 3D printing process in weightlessness. Finally, a Wordle player used a 3D printer and a Raspberry Pi card to automate the game.

TUM and Oerlikon found the Advanced Manufacturing Institute

Representatives of the Technical University of Munich (TUM) and Oerlikon (Image courtesy of Oerlikon via LinkedIn)

Together, the Technical University of Munich (TUM) and Swiss engineering and technology group Orlikon will be jointly found an advanced manufacturing institute in order to pilot 3D printing and master the challenges of industrialization. For the first five years, the TUM-Oerlikon Advanced Manufacturing Institute, based on the TUM campus, will be funded with an annual budget of 3 million euros. Also during these five years, up to thirty theses will be supervised which will focus on technical research of the entire AM value chain, including new materials, the printing process itself and the interactions between the two.

“Our research efforts are primarily focused on technical challenges that, once overcome, will accelerate the development of metal 3D printing,” explained Dr. Nikolaus A. Adams, Director of the Chair of Aerodynamics and of fluid mechanics at TUM, about the research. projects. “For example, we are already working together on new high-strength aluminum-based lightweight alloys in high demand in industry, on new demanding simulation techniques to predict the melting and solidification process of metal powders and on the development of a digital certification process using components produced for the aerospace industry using state-of-the-art manufacturing.

Fluicell launches a new bioprinter

Swedish Biotechnology Company Fluid presented its single-cell bioprinting system, the Biopixlarin 2019. This month, it spear the Biopixlar AER, a new automated and portable high-resolution single-cell bioprinter. The microfluidic platform is compact enough to fit in a standard cell culture flow hood, making it easy to use with other 3D cell culture technologies. The new Biopixlar AER also offers remote control. All of these features combine to create a system well suited for demanding workflows, such as deep-sea exploration and aerospace applications.

“Biopixlar AER is truly a groundbreaking technological advancement, representing a product offering that is fully in line with our overall aspiration and philosophy to combine biology and technology to meet future healthcare needs,” said Victoire. Viannay, CEO of Fluicell. “Biopixlar AER fits perfectly with Fluicell’s strategy to make a difference for researchers by increasing the flexibility, performance and adaptability of bioprinting. Biopixlar AER is also targeting new customer segments that emphasize the ability to parallelize and automate bioprinting and cell culture processes.

New six-axis robotic bio-printer

New six-axis robotic bio-printing system and its printing products. A. Six-axis robotic bioprinting platform and the printed IGDB letters composed of eGFP-labeled endothelial cells; B. The bioprinted artificial blood vessel is able to form new capillaries (left and middle, green color corresponds to eGFP-labeled endothelial cells). Bioprinted vascularized heart tissue (right, green color is heart tissue and red color is vascular network); C. The two-robot cooperation platform (left) can simultaneously imprint different cell types on a complex-shaped vascular scaffold (middle) to form a patterned cell organization (right). (Image: IGDB)

A collaborative team of researchers from Institute of Genetics and Developmental Biology from chinese academy of sciencesthe University of Manchesterand Tsinghua University published a study detailing their work by developing a new 3D bioprinting platform. The researchers converted a six-axis robotic arm into a bio-printer, which made it possible to print cells in all directions. They did this by combining the bioprinter with an oil-bath cell printing system, which printed a complex scaffold of blood vessels without damaging the cells or compromising their function.

The natural organ development process inspired the team to implement a repeated strategy of cell printing and biological cultivation. This could potentially generate complex tissues and organs, with 3D-printed cells connecting to networks of blood vessels. The researchers demonstrated that their technique was feasible by printing bio-inks of endothelial cells and cardiomyocytes onto blood vessel scaffolds. In this way, they generated a piece of vascularized heart tissue that stayed alive and beating for at least six months.

CELLINK, CollPlant High-end production of regenerative breast implants

3D bio-printed breast implant produced by CollPlant and currently used in preclinical studies.

In continuing bioprinting news, the leader in bioprinting CELLINKa BICO Group society, and regenerative and aesthetic medicine society CollPlant Biotechnology to have concluded a collaboration. Together, they will explore the use of CELLINK’s high-throughput multi-material bioprinters for the future large-scale production of CollPlant’s regenerative breast implants. CollPlant uses its rhCollagen and other biological components to manufacture 3D bio-printed implant prototypes intended to regenerate breast tissue. Currently being evaluated in preclinical studies, these regenerative implants have been designed to gradually degrade and be replaced by new, natural breast tissue. Thanks to CELLINK’s expertise and its large-scale bioprinting production process, it will be able to help CollPlant continue these important studies.

“We are very pleased to partner with CELLINK, a recognized leader in the development of 3D bioprinting solutions for the life science industry. We believe that CELLINK’s high-throughput bioprinters and biofabrication expertise will help us move forward towards the successful commercialization of our technology and provide a much-needed solution to patients around the world,” said Yehiel Tal, CEO of CollPlant.

NINJAS tests a new 3D printing process in weightlessness

Team NINJAS tests its 3D printing process during a weightless test flight. (Image courtesy of Hantang Qin)

Moving on, Iowa State University the research team NINJAS, which stands for No-Gravity Ink Jet Printing for Aeronautics and Space, has successfully tested a new 3D printing process that works in weightlessness. They saw a need for zero-g 3D printing in long-term space exploration and developed the process at university Flexible Electronics and Additive Printing Laboratory (FEAP). One group of researchers created the printer itself, which sets ink with electrical force instead of gravity, while another group developed patent-pending silver and titanate inks. of barium. Researchers tested the printer and inks at Fort Lauderdale International Airport, the Zero Gravity Corporation research center. In addition to battling environmental motion sickness, Team NINJAS learned a lot during the three-day testing period.

“[The] first day gave us a really valuable experience. We achieved some things that we hadn’t done 100%,” explained Shan Jiang, assistant professor of materials science and engineering and one of the co-principal investigators. “The second and third days went very well. We have printed lovely patterns. It was the first time we proved that our 3D technology and nano ink can be used in a zero g environment.

3D printer and Raspberry Pi used to automate Wordle

Finally, unless you’ve been living under a rock for the past few months, you’ve probably heard of wordle. The guessing game, developed by a software engineer and later purchased by The New York Times, gives players six chances to guess the correct five-letter word of the day. Everyone has their own strategies for winning, but the Reddit user iamflimflam1 took things to the next level by automate the game. Using a 3D printer as a robot and a Raspberry Pi for image processing and puzzle solving, the creation can solve the Wordle puzzle in less than a minute! The two big challenges are said to be locating the phone screen and the printer bed, and the printing speed has been set as high as possible in order to type the letters very quickly.

“Once we have the locations of these two objects, we can create a transformation from locations on the phone screen to locations in the grabbed image. And then we can create a transform from the grabbed image to locations on the printer bed”, iamflimflam1 wrote.

“These two transformations allow us to tell the printer where to move so that it can touch the keys on the screen. Reading the colors of the guessed word is quite simple, because we know where the grid squares are on the phone screen, and since we have the transformation, we know where the grid squares are in the image capture.

The source code for this creation was published on GitHub if you want to try it. See the automated Wordle game in action below: